Karlayne is from West Columbia, SC and has lived in Charleston for the past 20 years. She received her Bachelor's of Science in Nursing and Masters of Science in Nursing as a Pediatric Nurse Practitioner from MUSC. She worked at MUSC for 18 years between the Neonatal Intensive Care Unit and Child Abuse Pediatrics. She has also taught undergraduate nursing at Trident Tech and MUSC College of Nursing.
She and her husband Tari have two sons and a Boston Terrier, Dooney. They enjoy going to the beach, traveling, and watching sports, especially football!